International Journal of Advanced Chemistry Research

International Journal of Advanced Chemistry Research

Online ISSN: 2664-679X
Print ISSN: 2664-6781

International Journal of Advanced Chemistry Research
Online and Print Journal   |   Indexed Journal   |   Refereed Journal   |   Peer Reviewed Journal
International Journal of Advanced Chemistry Research
2019, Vol. 1, Issue 1
A mini review diverse biological activities of heterocyclic indole analogues

Mohammad Asif, Abida, Md Tauquir Alam

Various heterocyclic analogues were found to possess promising pharmacological activities. Various indole analogues are also attracted the attention of researchers because of the diverse biological activities. Indole nucleus is present in many natural as well as synthetic products. Due to its wider applications the indole analogues, they will replace many existing heterocyclic based pharmaceutical products. Now days, various drugs are in market and several are in clinical trials. Various indole analogues were identified as a privileged structure of pharmacophore and possess broad spectrum of biological and pharmaceutical activities such as anticancer, antihypertensive, antidepressant, antipsychotic, anti-inflammatory, antiemetic, analgesic, anti-asthmatic, antiviral, anti-arrhythmic, β-blocker, inhibitor of RNA polymerase-11, agonist for the cannabinoid receptor, non- nucleoside reverse transcriptase inhibitor, opioid agonist and sexual dysfunction etc. Indole derivatives have been special interest to organic and medicinal chemists.
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