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International Journal of Advanced Chemistry Research

Vol. 5, Issue 1, Part A (2023)

Biologically important 26-32-membered macrocyclic complexes of manganese (II): In situ one pot template synthesis (IOPTS), characterization and bio-efficacy

Author(s):

Mamta, Anita Phor, JS Phor and Ashu Chaudhary

Abstract:

Twenty six to thirty two membered tetraazamacrocyclic complexes of manganese (II) have been synthesized by template condensation of MnCl2.4H2O with dicarboxylic acid (malonic, succinic, glutaric or adipic acid) and 1,8-diaminooctane in 1:2:2 molar ratios. The new products with octahedral geometry have been characterized by elemental analyses, molecular weight determinations, molar conductance, magnetic moment and spectral studies viz., infrared and electronic. On the basis of the spectral studies the binding sites are proposed as the nitrogen atom of the macrocycles. The formulation of the complexes as [Mn(Macn)Cl2] (where n = 1 - 4) has been established on the basis of chemical composition. To assess the growth inhibiting potential of the manganese (II) complexes biological screening has been undertaken.

Pages: 06-09  |  299 Views  85 Downloads


International Journal of Advanced Chemistry Research
How to cite this article:
Mamta, Anita Phor, JS Phor and Ashu Chaudhary. Biologically important 26-32-membered macrocyclic complexes of manganese (II): In situ one pot template synthesis (IOPTS), characterization and bio-efficacy. Int. J. Adv. Chem. Res. 2023;5(1):06-09. DOI: 10.33545/26646781.2023.v5.i1a.136
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