Vol. 7, Issue 10, Part A (2025)

Oral rehydration solutions (ORS) play a crucial role in the prevention and treatment of dehydration resulting from diarrhea, vomiting, and other fluid-loss conditions, particularly in children and vulnerable populations. While commercially available ORS formulations are widely used and clinically effective, they may not always be accessible or cost-effective in resource-limited settings. Recently, attention has shifted towards natural electrolyte sources, such as coconut water and banana powder, which are rich in essential electrolytes (sodium, potassium, magnesium) and carbohydrates, offering not only hydration but also nutritional benefits.

The present study aimed to develop a laboratory-formulated ORS using these natural ingredients and to compare its physicochemical properties with those of commercially available ORS products. Parameters evaluated included pH, osmolarity, electrical conductivity, and stability under different storage conditions. Laboratory-prepared ORS demonstrated physicochemical properties comparable to marketed formulations, with slight improvements in certain parameters such as pH buffering and electrolyte balance. Stability studies indicated that the natural formulations remained stable over a 30-day period without significant changes in appearance, pH, or conductivity.