Vol. 7, Issue 3, Part A (2025)

With growing attention to environmental sustainability in analytical sciences, this study presents an eco-friendly UV spectrophotometric method for Chlorpheniramine maleate. This method is simple, precise, accurate, reproducible, eco-friendly as well as sensitive. The method has been optimized and validated using Water as a diluent, shows no interference. UV-Visible model 1800 was used for the analysis and maximum absorbance (λ_max) measured at 223 nm against blank solution. Important validation parameters validated. Results show high accuracy with recovery between 95% to 105% and precision with an RSD below 1.0% across multiple trials. The linearity noticed between the concentration range i.e. 8-24 µg/ml with correlation coefficient in limit. This eco-friendly method demonstrates reliability for routine regular analysis in pharmaceutical industries in Quality Control, stability while reducing environmental impact.